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Vancomycin: Glycopeptide Antibiotic for Advanced MRSA & G...
2025-10-05
Vancomycin’s precise D-Ala-D-Ala binding unlocks unparalleled control in modeling bacterial resistance and gut-immune dynamics. This guide delivers actionable protocols, troubleshooting insights, and strategic applications for leveraging Vancomycin in MRSA, C. difficile, and microbiome studies.
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Vancomycin in Translational Research: Mechanistic Depth a...
2025-10-04
This thought-leadership article provides translational researchers with advanced mechanistic insights and actionable strategies for leveraging Vancomycin—a gold-standard glycopeptide antibiotic—in experimental models of bacterial resistance, MRSA, Clostridium difficile infections, and immune-microbiome modulation. By integrating biological rationale, experimental validation (including findings from recent immune-microbiome studies), and forward-looking translational perspectives, the article positions Vancomycin not just as a research reagent but as a precision tool for breakthrough discovery.
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Vancomycin as a Precision Tool: Reimagining Glycopeptide ...
2025-10-03
This thought-leadership article positions Vancomycin not just as a cornerstone glycopeptide antibiotic, but as a strategic instrument for unraveling bacterial cell wall synthesis, resistance mechanisms, and microbiome-immune interactions. We integrate mechanistic clarity, highlight recent experimental models—including immune-microbiome modulation in allergic rhinitis—and provide strategic guidance for translational researchers seeking to innovate beyond conventional approaches. By contextualizing Vancomycin’s value in preclinical and systems-level studies, we empower researchers to leverage this agent in ways that transcend routine antibacterial applications.
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Vancomycin in Precision Microbiome and Immunity Modelling
2025-10-02
Explore Vancomycin as a glycopeptide antibiotic and bacterial cell wall synthesis inhibitor in advanced MRSA and Clostridium difficile infection research. This article uniquely integrates technical applications with novel immune-microbiome modelling approaches for translational biomedical studies.
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Vancomycin at the Interface of Bacterial Resistance and T...
2025-10-01
This thought-leadership article explores Vancomycin’s unique role as a glycopeptide antibiotic and bacterial cell wall synthesis inhibitor in contemporary translational research. By integrating mechanistic insights, experimental paradigms, and immunological dimensions, we offer strategic guidance for researchers aiming to unravel bacterial resistance mechanisms, modulate the microbiome, and bridge preclinical discoveries with human health applications. The discussion draws on recent immunology-microbiome research and positions Vancomycin as a precision tool for experimental innovation.
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Vancomycin: A Precision Tool for Deciphering Bacterial Re...
2025-09-30
Explore the unique capabilities of Vancomycin as a glycopeptide antibiotic in unraveling bacterial cell wall synthesis and resistance mechanisms. This in-depth article examines Vancomycin’s advanced utility in MRSA and Clostridium difficile infection research, with a special focus on gut-immune interplay and experimental design.
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Vancomycin as a Molecular Probe: Advancing Gut-Immune Axi...
2025-09-29
Discover how Vancomycin, a potent glycopeptide antibiotic, enables next-generation studies on bacterial cell wall synthesis inhibition, gut-immune axis modulation, and resistance mechanisms. This article uniquely bridges molecular action with experimental strategies in microbiota and immune research.
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Vancomycin in Experimental Microbial Ecology: Unveiling R...
2025-09-28
Explore Vancomycin's role as a glycopeptide antibiotic in advancing experimental microbial ecology and antibacterial agent research for MRSA and Clostridium difficile. This article uniquely bridges cell wall synthesis inhibition with immunological and microbiome dynamics, offering new insights for resistance mechanism studies.
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Vancomycin in Research: Mechanisms, Microbiome, and Immun...
2025-09-27
Explore how Vancomycin, a premier glycopeptide antibiotic, uniquely informs bacterial resistance mechanism studies and microbiome-immune research. This article provides deeper scientific analysis and novel experimental perspectives beyond traditional applications.
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c-Myc Tag Peptide: Precision Tools for Dissecting Transcr...
2025-09-26
Explore the scientific power of the c-Myc tag peptide as a synthetic research reagent for cancer biology. This article reveals unique mechanistic insights into transcription factor regulation, autophagy, and advanced immunoassay strategies.
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Z-VAD-FMK in Apoptotic and Ferroptotic Resistance: Advanc...
2025-09-25
Explore how Z-VAD-FMK, a cell-permeable pan-caspase inhibitor, is revolutionizing apoptosis and ferroptosis research. This in-depth article uniquely bridges apoptotic pathway inhibition with emerging insights into regulated cell death resistance in cancer and neurodegenerative models.
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Angiotensin II: Unraveling Senescence Pathways in AAA and...
2025-09-24
Discover how Angiotensin II, a potent vasopressor and GPCR agonist, uniquely enables advanced research into vascular senescence and abdominal aortic aneurysm pathophysiology. Explore in-depth mechanisms, cutting-edge applications, and translational insights distinct from traditional approaches.
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Phosbind Acrylamide: Enabling Antibody-Free Analysis of M...
2025-09-23
Phosbind Acrylamide, a phosphate-binding reagent, advances phosphorylated protein detection by enabling precise electrophoretic separation and analysis of phosphorylation status without phospho-specific antibodies. This article explores its unique role in dissecting multisite phosphorylation events in cell signaling pathways.
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In large biopsies series from ALK NSCLC treated patients the
2025-03-03

In large biopsies series from ALK+ NSCLC treated patients, the number of detected mutations increased after second generation ALKi (Gainor et al., 2016) and in one study were present in 56% of the entire cohort (Shaw et al., 2013b). For example, the rate of G1202R mutations increases from 2% in post
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Our study like that of Zill et al included
2025-03-03

Our study, like that of Zill et al. (2012) included European Caucasians, although their population was much smaller (n=162) and more heterogeneous (19–72years). Further, potential confounding or effect modification by other health, lifestyle or genetic factors was not considered. These differences m
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